安徽医科大学徐涛教授课题组介绍
徐涛
博士,副教授,安徽医科大学硕士生导师。
发表SCI论文100余篇,其中第一作者和通讯作者60余篇。
兼任Clinical Gastroenterologist International编委、
Frontiers in Pharmacology客座主编,
Frontiers in Cell and Developmental Biology客座编辑,
浙江省自然科学基金评审专家
研究方向:
肝脏炎症的机制研究、酒精性肝病发病机制、医院人文等。
主持课题:
1.国家自然科学基金青年基金 “TMEM88调控酒精性肝病中炎症因子分泌的功能和机制研究” 2018/01-2020/12
2.安徽省自然科学基金面上项目2018/07-2021/6
3.安徽省高校自然科学基金重点项目“基于Wnt/β-catenin通路探讨TMEM88甲基化在肝纤维化中的作用及其调控机制” 2016/01-2018/12
4.安徽医科大学博士科研基金XJ201536
5.2020年安徽省经济社会发展重大课题“加快补齐安徽医疗卫生服务体系短板研究”
6.2020年合肥市政府重大课题“合肥生命健康产业研究”
作为项目参与人申请获得国家自然科学基金面上项目4项。
部分发表文章:
- Xu,T., Li, L., Huang, C., Li, X., Peng, Y. & Li, J. (2013) MicroRNA-323-3p with clinical potential in rheumatoid arthritis, Alzheimer's disease and ectopic pregnancy, Expert opinion on therapeutic targets. 18, 153-82.
- Xu, T, Ni, M. M, Meng, X. M., Huang, C., He, Y. H. & Li, J. (2015) NLRC5 mediates cytokine secretion in LX-2 cells and modulated by the NF-κB/Smad3 pathway. Inflammation DOI:10.1007/s10753-015-0157-6
- Xu, T, Ni, M. M, Meng, X. M., Huang, C., He, Y. H. & Li, J. (2015) NLRC5 regulates TGF-β1-induced proliferation and activation of hepatic stellate cells during hepatic fibrosis. International Journal of Biochemistry and Cell Biology DOI:10.1016/j.biocel.2015.11.010
- Ge, Yun-Xuan,Wang, Chang-Hui,Hu, Fu-Yong,Pan, Lin-Xin,Min, Jie,Niu, Kai-Yuan,Zhang, Lei,Li, Jun,Xu, Tao*,New advances of TMEM88 in cancer initiation and progression, with special emphasis on Wnt signaling pathway.,J Cell Physiol,2017.2.9
- Hu J, Li P, Song Y, Ge YX, Meng XM, Huang C, Li J, Xu T*.Progress and Prospects of Circular RNAs in Hepatocellular Carcinoma: Novel insights into their function.J Cell Physiol. 2017 Aug 19. doi: 10.1002/jcp.26154. Cover Image, Volume 233, Number 6, June 2018.Hu J, Li P, Song Y, Ge YX, Meng XM, Huang C, Li J, Xu T.J Cell Physiol. 2018 Jun;233(6):i. doi: 10.1002/jcp.26534.PMID: 29485203
- Huang C., Lv X.-w., Xu T., Ni M.-m., Xia J.-l., Cai S.-p., Zhou Q., Li X., YangY., Zhang L., Yao H.-w., Meng X.-m., Wang H. & Li J., Alcohol use in Hefei in relation to alcoholic liverdisease: a multivariate logistic regression analysis, Alcohol (2017), doi: 10.1016/j.alcohol.2017.08.001
- Tao Xu, Chang-ming Lin, Shu-qi Cheng, Jie Min, Li Li, Xiao-ming Meng, Cheng Huang, Lei Zhang,Zi-yu Deng. Jun Li Pathological Bases and Clinical Impact of Long noncoding RNAs in Prostate Cancer: A New Budding Star, Molecular Cancer 2018 Jul 23;17(1):103. DOI: 10.1186/s12943-018-0852-7
- 徐涛,程淑琪,李丽,李俊,邵东华.安徽省公立医院人文关怀制度试点医院建设研究[J].中国医学伦理学,2019,32(08):1047-1051.
- Zhang L, Meng X, Zhu XW, Yang DC, Chen R, Jiang Y, Xu T*.Long non-coding RNAs in Oral squamous cell carcinoma: biologic function, mechanisms and clinical implications.Mol Cancer. 2019 May 27;18(1):102. doi: 10.1186/s12943-019-1021-3.
- Xu T, Pan L, Li L, Hu S, Zhou H, Yang C, Yang J, Li H, Liu Y, Meng X and Li J. MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88. J Cell Mol Med 2020 May 28;24(13):7127-7140. doi: 10.1111/jcmm.15119.